SERN | Southeast NBS & Genetics Regional Collaborative

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Laboratory Performance Workgroup


Laboratory performance lies at the heart of public health's successful newborn screening (NBS) system.  The Laboratory Performance Workgroup was established to aid in the maintainance and continuous improvement of the already strong laboratory system in the southeast United States.  Specifically, the overall aim of the workgroup will be to decrease and sustain the lowest possible false-positive rate (FPR) and to increase positive predictive value (PPV), while optimizing detection and diagnosis rates and improving the standardization of confirmatory testing for all conditions detected. These efforts will then be expanded to explore second-tier testing and the development of tools and resources for quality assurance and quality control (QA/QC) with the aim of improving laboratory performance.

The laboratory performance workgroup is partnering with the emergency preparedness workgroup to develop an EP plan for the southeast region newborn screening laboratories. Additionally the workgroup is coordinating with the workforce capacity workgroup to help develop web based tutorials for the assays used in clinical biochemical laboratory testing.


Tim Wood, PhD, Chair


Workgroup Projects

Sample Exchange

The sample exchange is a peer-to-peer anonymous sample sharing program aimed at improving regional knowledge about TMS screened conditions and local data harmonization within the region; and evaluating the degree of analytical correlation between laboratories.

Due to the sensitive nature of this program, only approved users have access to the database.

If you are unable to gain access and believe that this is an error, please contact the system administrator for assistance.


SERN Highlights
February 2018

2018 Annual Meeting for SERN/SERGG - July 19-21 in Asheville, NC

2018 Annual Meeting for SERN/SERGG - July 19-21 in Asheville, NC

The next annual SERN/SERGG meeting will be held July 19-21, 2018 at Renaissance Asheville Hotel in Asheville, NC.

More information available on the SERGG website:

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